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An evaluation by rat colon anastomosis of the efficacy of fibrin glue derived from snake venom J. Venom. Anim. Toxins
LEITE,C.V.S.; NARESSE,L.E.; ARANTES,H.L.; LOPES,A.F.; THOMAZINI-SANTOS,I.A.; GIANNINI,M.J.S; MERCADANTE,M.C.; BARRAVIERA,B.; KOBAYASI,S..
The objective of this study was to evaluate the efficacy of fibrin adhesive made up of snake venom and bubaline fibrinogen by rat colon anastomosis. Eighty rats were randomly assigned into 2 experimental groups: GI control (anastomosis with extramucous interrupted suture) and GII (repair suture + fibrin glue). The animals were studied at the following 4 times: T0 – preoperative, T1 – 7th day postoperative, T2 – 14th day postoperative, and T3 – 21 st day postoperative. The macroscopic characteristics of the intestinal segment open and closed anastomosis and the bursting strength of the anastomosed segments were observed at each of the above times. The results showed that the anastomosed segments coapted and there was no difference in the bursting strength...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Fibrin glue; Experimental healing; Bursting strength; Experimental anastomosis; Snake venom; Colon anastomosis.
Ano: 2000 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79302000000200004
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